Description
Product Characteristics: Protein phosphatase 3, catalytic subunit, alpha isozymeis aproteinthat in humans is encoded by thePPP3CAgene. Calcium-dependent, calmodulin-stimulated protein phosphatase. Many of the substrates contain a PxIxIT motif. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates DNM1L, HSPB1 and SSH1.
Target Information: catalytic subunit of Calcineurin (CaN), ubiquitously expressed Ca2+\\/CaM-dependent protein phosphatase\\\\, mediates activities of transcription factors and ion channels\\\\, involved in regulation of T-cell activation [RGD, Feb 2006]